Compound Q&A

How is Dasabuvir (CAS: 1132935-63-7) typically synthesized?

Answer

Dasabuvir
Dasabuvir is synthesized through a multi-step process involving protection of the hydroxyl group, coupling with an amine, and subsequent deprotection. Commonly used catalysts include palladium and other transition metals. The overall yield is around 60%, with high selectivity towards the desired product.

About

English Name Dasabuvir
Molecular Formula C26H27N3O5S
Molecular Weight 493.59 g/mol
SMILES CC(C)(C)C1=CC(=CC(=C1OC)C2=CC3=C(C=C2)C=C(C=C3)NS(=O)(=O)C)N4C=CC(=O)NC4=O
InChIKey NBRBXGKOEOGLOI-UHFFFAOYSA-N
Last Updated: 2025-10-19 20:30

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