Compound Q&A
How is 4-Bromo-6-methylpyrimidine (CAS: 69543-98-2) typically synthesized?
Answer
4-Bromo-6-methylpyrimidine is typically synthesized by bromination of 6-methylpyrimidine using N-bromosuccinimide (NBS) in the presence of a suitable catalyst like benzoyl peroxide under anhydrous conditions. The reaction yields a high percentage of the desired product with good selectivity. The process involves careful monitoring to ensure the desired bromination occurs at the correct position.
About
CAS No
69543-98-2
English Name
4-Bromo-6-methylpyrimidine
Molecular Formula
C5H5BrN2
Molecular Weight
173.01 g/mol
EINECS
205-525-8
SMILES
CC1=CC(=NC=N1)Br
InChIKey
GBPCCNWUSHSRTM-UHFFFAOYSA-N
Last Updated: 2025-10-19 20:30
