Compound Q&A
How is 2-Bromo-4-methyl-1,3-thiazole-5-carboxylic acid (CAS: 40003-41-6) typically synthesized?
Answer
2-Bromo-4-methyl-1,3-thiazole-5-carboxylic acid is typically synthesized via the bromination of 4-methyl-1,3-thiazole-5-carboxylic acid. The reaction involves the use of N-bromosuccinimide (NBS) in an organic solvent such as dichloromethane. The yield is generally good, and selectivity is high. Proper handling of NBS and the organic solvent is crucial to prevent fire hazards.
About
CAS No
40003-41-6
English Name
2-Bromo-4-methyl-1,3-thiazole-5-carboxylic acid
Molecular Formula
C5H4BrNO2S
Molecular Weight
222.063 g/mol
SMILES
CC1=C(SC(=N1)Br)C(=O)O
InChIKey
HMSQZHBSTZZNGI-UHFFFAOYSA-N
Last Updated: 2025-10-19 20:30
