Compound Q&A
How is Ethyl 2-pyrimidinylacetate (CAS: 63155-11-3) typically synthesized?
Answer
Ethyl 2-pyrimidinylacetate (CAS: 63155-11-3) is typically synthesized via the condensation of 2-pyrimidinylacetic acid with ethyl bromide in the presence of a base such as potassium carbonate. The reaction is carried out in an aprotic solvent like dimethylformamide (DMF) under mild heating. The yield is usually around 70-80%, and the product can be purified by recrystallization from organic solvents.
About
CAS No
63155-11-3
English Name
Ethyl 2-pyrimidinylacetate
Molecular Formula
C8H10N2O2
Molecular Weight
166.18 g/mol
SMILES
CCOC(=O)CC1=NC=CC=N1
InChIKey
DZQZAEMLHNEMEN-UHFFFAOYSA-N
Last Updated: 2025-10-19 20:30
