How is 2-Methoxy-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridine (CAS: 445264-61-9) typically synthesized?

2-Methoxy-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridine is typically synthesized via a cross-coupling reaction. The synthesis involves the reaction of 5-bromopyridine with a boronic acid ester in the presence of a phase transfer catalyst like tetrabutylammonium fluoride (TBAF) and a base like triethylamine. The yield is generally high, and the reaction is known for its high regioselectivity and tolerance of functional groups.