Compound Q&A

How is 5-Nitro-2(1H)-pyrimidinone (CAS: 3264-10-6) typically synthesized?

Answer

5-Nitro-2(1H)-pyrimidinone
5-Nitro-2(1H)-pyrimidinone can be synthesized via nitration of 2(1H)-pyrimidinone. Commonly, this involves treating pyrimidinone with nitric acid in the presence of an acid catalyst such as sulfuric acid. The reaction is carried out at room temperature, and yields up to 85% are achievable. High selectivity is maintained under these conditions.

About

CAS No 3264-10-6
English Name 5-Nitro-2(1H)-pyrimidinone
Molecular Formula C4H3N3O3
Molecular Weight 141.09 g/mol
SMILES C1=C(C=NC(=O)N1)[N+](=O)[O-]
InChIKey ZNNRVSOVVLYQBV-UHFFFAOYSA-N
Last Updated: 2025-10-19 20:30

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