Compound Q&A

How is 2,2,2-Trifluoroethanol (CAS: 77253-67-9) typically synthesized?

Answer

2,2,2-Trifluoro(~2~H_2_)ethan(~2~H)ol
2,2,2-Trifluoroethanol (CAS: 77253-67-9) is commonly synthesized via hydroboration of 2,2,2-trifluoroethene followed by oxidation. The reaction typically uses diborane as the borane source and a suitable oxidizing agent like sodium hypochlorite or hydrogen peroxide. The yield is generally between 60-80%, and the method is known for its high selectivity towards 2,2,2-trifluoroethanol.

About

CAS No 77253-67-9
English Name 2,2,2-Trifluoro(~2~H_2_)ethan(~2~H)ol
Molecular Formula C2D3F3O
Molecular Weight 103.06 g/mol
SMILES C(C(F)(F)F)O
InChIKey RHQDFWAXVIIEBN-IDPMSXFZSA-N
Last Updated: 2025-10-19 20:29

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