Compound Q&A

How is 4-Isopropyl-2,2-dimethyl-1,3-benzodioxole (CAS: 201166-22-5) typically synthesized?

Answer

4-Isopropyl-2,2-dimethyl-1,3-benzodioxole
4-Isopropyl-2,2-dimethyl-1,3-benzodioxole (CAS: 201166-22-5) can be synthesized through a multistep process involving the protection of a hydroxyl group followed by ring expansion. Commonly, a starting material like 2,2-dimethyl-1,3-benzodioxole is reacted with isopropyl iodide in the presence of a base like potassium carbonate. The reaction typically yields high selectivity with good to excellent yields, making it a viable method for industrial production.

About

English Name 4-Isopropyl-2,2-dimethyl-1,3-benzodioxole
Molecular Formula C12H16O2
Molecular Weight 192.26 g/mol
SMILES CC1(C)OC2=CC=CC(C(C)C)=C2O1
InChIKey DHDJXCHGRUOYCV-UHFFFAOYSA-N
Last Updated: 2025-10-19 20:29

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