Compound Q&A

How is (3S,11aR)-N-(2,4-Difluorobenzyl)-6-hydroxy-3-methyl-5,7-dioxo-2,3,5,7,11,11a-hexahydro[1,3]oxazolo[3,2-a]pyrido[1,2-d]pyrazine-8-carboxamide (CAS: 1051375-10-0) typically synthesized?

Answer

(3S,11aR)-N-(2,4-Difluorobenzyl)-6-hydroxy-3-methyl-5,7-dioxo-2,3,5,7,11,11a-hexahydro[1,3]oxazolo[3,2-a]pyrido[1,2-d]pyrazine-8-carboxamide
This compound is synthesized via a multi-step process involving condensation reactions, amide formation, and functional group modifications. Key steps include the use of fluoride-containing benzyl derivatives and precise control of reaction conditions to achieve high yield and selectivity. The process often requires the use of catalysts such as palladium and specific bases for optimal results.

About

English Name (3S,11aR)-N-(2,4-Difluorobenzyl)-6-hydroxy-3-methyl-5,7-dioxo-2,3,5,7,11,11a-hexahydro[1,3]oxazolo[3,2-a]pyrido[1,2-d]pyrazine-8-carboxamide
Molecular Formula C19H17F2N3O5
Molecular Weight 405.35 g/mol
SMILES C[C@H]1CO[C@@H]2Cn3cc(C(=O)NCc4ccc(F)cc4F)c(=O)c(O)c3C(=O)N12
InChIKey WCWSTNLSLKSJPK-LKFCYVNXSA-N
Last Updated: 2025-10-19 20:29

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