Compound Q&A
How is (4R)-1-Palmitoyl-4-(palmitoyloxy)-L-proline (CAS: 41672-81-5) typically synthesized?
Answer
(4R)-1-Palmitoyl-4-(palmitoyloxy)-L-proline is usually synthesized through a multi-step process involving the succinylation of L-proline followed by esterification with palmitic acid. This reaction requires careful control of pH and temperature to achieve high selectivity and yield. Commonly used catalysts include HOBt and DMAP to improve the reaction efficiency.
About
CAS No
41672-81-5
English Name
(4R)-1-Palmitoyl-4-(palmitoyloxy)-L-proline
Molecular Formula
C37H69NO5
Molecular Weight
607.96 g/mol
SMILES
CCCCCCCCCCCCCCCC(=O)O[C@@H]1C[C@H](N(C1)C(=O)CCCCCCCCCCCCCCC)C(O)=O
InChIKey
QZLXCFQVOCEKSX-NOCHOARKSA-N
Last Updated: 2025-10-19 20:29
