Compound Q&A

How is 2,5-Dimethyl-1,3-benzoxazole (CAS: 5676-58-4) typically synthesized?

Answer

2,5-Dimethyl-1,3-benzoxazole
2,5-Dimethyl-1,3-benzoxazole (CAS: 5676-58-4) is commonly synthesized via the condensation of 2,5-dimethylbenzaldehyde with hydroxylamine hydrochloride. The reaction typically involves refluxing the mixture in an appropriate solvent such as ethanol or acetic acid. The yield is usually around 70-80%, and the use of a basic catalyst like sodium hydroxide can enhance the reaction efficiency. The product can be isolated by recrystallization from a suitable solvent.

About

CAS No 5676-58-4
English Name 2,5-Dimethyl-1,3-benzoxazole
Molecular Formula C9H9NO
Molecular Weight 147.18 g/mol
SMILES CC1=CC2=C(C=C1)OC(=N2)C
InChIKey XVQGFGKAPKEUFT-UHFFFAOYSA-N
Last Updated: 2025-10-19 13:36

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