Compound Q&A

How is 2-Chloro-6-fluoro-1,3-benzothiazole (CAS: 399-74-6) typically synthesized?

Answer

2-Chloro-6-fluoro-1,3-benzothiazole
2-Chloro-6-fluoro-1,3-benzothiazole is typically synthesized through a multi-step process involving the introduction of chlorine into a benzothiazole ring, followed by a fluorination step. Commonly, this involves reacting benzothiazole with thionyl chloride and then with fluorine gas or hydrogen fluoride. The reaction conditions are carefully controlled to achieve high yields and good selectivity.

About

CAS No 399-74-6
English Name 2-Chloro-6-fluoro-1,3-benzothiazole
Molecular Formula C7H3ClFNS
Molecular Weight 187.63 g/mol
SMILES C1=CC2=C(C=C1F)SC(=N2)Cl
InChIKey ISIIQFDYFMPPOA-UHFFFAOYSA-N
Last Updated: 2025-10-19 13:36

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