Compound Q&A
How is Methyl (2E)-3-{3-[(cyclohexylcarbonyl){[4'-(dimethylamino)-4-biphenylyl]methyl}amino]phenyl}acrylate (CAS: 574013-66-4) typically synthesized?
Answer
![Methyl (2E)-3-{3-[(cyclohexylcarbonyl){[4'-(dimethylamino)-4-biphenylyl]methyl}amino]phenyl}acrylate](https://static.chemtradehub.com/structs/574/574013-66-4-a2e5.webp "Methyl (2E)-3-{3-[(cyclohexylcarbonyl){[4'-(dimethylamino)-4-biphenylyl]methyl}amino]phenyl}acrylate")
Methyl (2E)-3-{3-[(cyclohexylcarbonyl){[4'-(dimethylamino)-4-biphenylyl]methyl}amino]phenyl}acrylate is synthesized via a multi-step process involving the coupling of a cyclohexylcarbonyl derivative with a 4'-(dimethylamino)-4-biphenylyl methylamine. The reaction often requires the use of a palladium catalyst and is typically carried out under microwave conditions to enhance yield and selectivity. The overall yield of the reaction is around 70-80%.
About
CAS No
574013-66-4
English Name
Methyl (2E)-3-{3-[(cyclohexylcarbonyl){[4'-(dimethylamino)-4-biphenylyl]methyl}amino]phenyl}acrylate
Molecular Formula
C32H36N2O3
Molecular Weight
496.65 g/mol
SMILES
CN(C)C1=CC=C(C=C1)C2=CC=C(C=C2)CN(C3=CC=CC(=C3)C=CC(=O)OC)C(=O)C4CCCCC4
InChIKey
VLQTUNDJHLEFEQ-KGENOOAVSA-N
Last Updated: 2025-10-19 13:36
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