Compound Q&A

How is 4-(2,3-Dimethylbenzyl)-1H-imidazole (CAS: 76631-46-4) typically synthesized?

Answer

4-(2,3-Dimethylbenzyl)-1H-imidazole
4-(2,3-Dimethylbenzyl)-1H-imidazole (CAS: 76631-46-4) is commonly synthesized via the coupling of 2,3-dimethylbenzyl bromide with imidazole. This reaction typically involves the use of a base like potassium carbonate and proceeds in an aprotic solvent such as N,N-dimethylformamide (DMF). The yield is around 85%, and the reaction is highly selective.

About

CAS No 76631-46-4
English Name 4-(2,3-Dimethylbenzyl)-1H-imidazole
Molecular Formula C12H14N2
Molecular Weight 186.26 g/mol
SMILES CC1=C(C(=CC=C1)CC2=CN=CN2)C
InChIKey RHDJRPPFURBGLQ-UHFFFAOYSA-N
Last Updated: 2025-10-19 13:36

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