Compound Q&A

How is 6-{[(2-Methyl-2-propanyl)oxy]carbonyl}-6-azaspiro[2.5]octane-1-carboxylic acid (CAS: 871727-05-8) typically synthesized?

Answer

6-{[(2-Methyl-2-propanyl)oxy]carbonyl}-6-azaspiro[2.5]octane-1-carboxylic acid
6-{[(2-Methyl-2-propanyl)oxy]carbonyl}-6-azaspiro[2.5]octane-1-carboxylic acid is synthesized via a multi-step process involving the protection of spiro lactam followed by acylation and deprotection. Commonly, a protected spiro compound is treated with a suitable acylating agent in the presence of a catalyst, followed by deprotection to yield the target product with high yield and good selectivity.

About

English Name 6-{[(2-Methyl-2-propanyl)oxy]carbonyl}-6-azaspiro[2.5]octane-1-carboxylic acid
Molecular Formula C13H21NO4
Molecular Weight 255.31 g/mol
SMILES CC(C)(C)OC(=O)N1CCC2(CC2C(=O)O)CC1
InChIKey ZVMOSXHYOPBSRN-UHFFFAOYSA-N
Last Updated: 2025-10-19 13:36

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