Compound Q&A

How is 5-(Chloromethyl)-1H-tetrazole (CAS: 55408-11-2) typically synthesized?

Answer

5-(Chloromethyl)-1H-tetrazole
5-(Chloromethyl)-1H-tetrazole (CAS: 55408-11-2) is typically synthesized by reacting chloromethyl ketone with hydrazine hydrate in the presence of an acid catalyst such as hydrochloric acid. The reaction involves condensation to form the tetrazole ring, with a yield of around 70-80%. The method is selective and efficient, making it a preferred route for industrial production.

About

CAS No 55408-11-2
English Name 5-(Chloromethyl)-1H-tetrazole
Molecular Formula C2H3ClN4
Molecular Weight 118.53 g/mol
SMILES C(C1=NNN=N1)Cl
InChIKey AGWSISOYPHROLN-UHFFFAOYSA-N
Last Updated: 2025-10-19 13:36

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