Compound Q&A

How is 2-Methyl-4-(trimethylsilyl)-3-butyn-2-ol (CAS: 5272-33-3) typically synthesized?

Answer

2-Methyl-4-(trimethylsilyl)-3-butyn-2-ol
2-Methyl-4-(trimethylsilyl)-3-butyn-2-ol (CAS: 5272-33-3) can be synthesized by the silylation of 2-methyl-3-butyn-2-ol using trimethylsilyl chloride in the presence of a base such as pyridine. The reaction is typically carried out under anhydrous conditions to avoid hydrolysis and dehydration reactions. The yield and selectivity of the reaction can be controlled by the choice of the base and the reaction conditions.

About

CAS No 5272-33-3
English Name 2-Methyl-4-(trimethylsilyl)-3-butyn-2-ol
Molecular Formula C8H16OSi
Molecular Weight 74.12 g/mol
SMILES CC(C)(C#C[Si](C)(C)C)O
InChIKey UXOWFNWZWBCLDN-UHFFFAOYSA-N
Last Updated: 2025-10-19 13:36

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