Compound Q&A

How is 4-Methoxy-1,3-benzothiazol-2(3H)-one (CAS: 80567-66-4) typically synthesized?

Answer

4-Methoxy-1,3-benzothiazol-2(3H)-one
4-Methoxy-1,3-benzothiazol-2(3H)-one can be synthesized via the condensation of benzothiazole and methanol in the presence of a suitable catalyst. Common methods include using acetic acid or p-toluenesulfonic acid as a catalyst, with a yield of around 80-90%. The reaction is typically carried out under mild conditions to ensure high selectivity.

About

CAS No 80567-66-4
English Name 4-Methoxy-1,3-benzothiazol-2(3H)-one
Molecular Formula C8H7NO2S
Molecular Weight 181.22 g/mol
SMILES COC1=C2C(=CC=C1)SC(=O)N2
InChIKey BOKIESUSRKISCV-UHFFFAOYSA-N
Last Updated: 2025-10-19 13:36

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