Compound Q&A

How is 3',6'-Diacetoxy-3-oxo-3H-spiro[2-benzofuran-1,9'-xanthene]-6-carboxylic acid (CAS: 3348-03-6) typically synthesized?

Answer

3',6'-Diacetoxy-3-oxo-3H-spiro[2-benzofuran-1,9'-xanthene]-6-carboxylic acid
3',6'-Diacetoxy-3-oxo-3H-spiro[2-benzofuran-1,9'-xanthene]-6-carboxylic acid is typically synthesized via a multi-step process involving acetoxylation of 2-benzofuran and subsequent spirocyclization with xanthene derivatives. The reaction is usually carried out under anhydrous conditions with a Lewis acid catalyst like aluminum chloride to achieve high selectivity and yield.

About

CAS No 3348-03-6
English Name 3',6'-Diacetoxy-3-oxo-3H-spiro[2-benzofuran-1,9'-xanthene]-6-carboxylic acid
Molecular Formula C25H16O9
Molecular Weight 460.39 g/mol
SMILES CC(=O)OC1=CC2=C(C=C1)C3(C4=C(O2)C=C(C=C4)OC(=O)C)C5=C(C=CC(=C5)C(=O)O)C(=O)O3
InChIKey QMOGCCYGOPYYNT-UHFFFAOYSA-N
Last Updated: 2025-10-19 13:36

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