Compound Q&A

How is 2-(2,6-Difluorophenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane (CAS: 863868-37-5) typically synthesized?

Answer

2-(2,6-Difluorophenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane
2-(2,6-Difluorophenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane is typically synthesized via a boronation reaction of 2,6-difluorophenylboronic acid with tetramethyl-1,3,2-dioxaborolane in the presence of a palladium catalyst and a base. The reaction is highly selective and yields a high product purity.

About

English Name 2-(2,6-Difluorophenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane
Molecular Formula C12H15BF2O2
Molecular Weight 240.06 g/mol
SMILES CC1(C)OB(OC1(C)C)c2c(F)cccc2F
InChIKey ADHKLRLGCVHQCG-UHFFFAOYSA-N
Last Updated: 2025-10-19 13:36

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