Compound Q&A
How is (4aR,7aR)-Octahydro-1H-pyrrolo[3,4-b]pyridine (CAS: 147459-51-6) typically synthesized?
Answer
![(4aR,7aR)-Octahydro-1H-pyrrolo[3,4-b]pyridine](https://static.chemtradehub.com/structs/147/147459-51-6-ade0.webp "(4aR,7aR)-Octahydro-1H-pyrrolo[3,4-b]pyridine")
(4aR,7aR)-Octahydro-1H-pyrrolo[3,4-b]pyridine can be synthesized via the Mannich reaction, where a pyrrole derivative is treated with an aldehyde and a base in the presence of a catalyst. This method provides good selectivity and high yield. The reaction is typically carried out under mild conditions, and the product can be isolated by column chromatography.
About
CAS No
147459-51-6
English Name
(4aR,7aR)-Octahydro-1H-pyrrolo[3,4-b]pyridine
Molecular Formula
C7H14N2
Molecular Weight
126.2 g/mol
SMILES
C1CC2CNCC2NC1
InChIKey
KSCPLKVBWDOSAI-RQJHMYQMSA-N
Last Updated: 2025-10-19 13:36
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