Compound Q&A
Are there alternatives to 5'-DMT-3'-TBDMS-Bz-rA (CAS: 81256-88-4) in synthesis?
Answer
There are several alternatives to 5'-DMT-3'-TBDMS-Bz-rA (CAS: 81256-88-4) that can be used in synthesis, depending on specific requirements. Common substitutes include 5'-DMT-3'-TBDMS-dT and 5'-DMT-3'-TBDMS-dG, which are often used as nucleobase precursors in nucleic acid synthesis. Other alternatives include using unprotected nucleosides or different protecting groups, such as Bz (benzoyl) or other common groups like Trityl (Trt) or Boc (tert-butoxycarbonyl), based on the desired end-application.
About
CAS No
81256-88-4
English Name
5'-DMT-3'-TBDMS-Bz-rA
Molecular Formula
C44H49N5O7Si
Molecular Weight
787.99 g/mol
SMILES
COC1=CC=C(C(C2=CC=CC=C2)(OC[C@@H]3[C@@H](O[Si](C)(C)C(C)(C)C)[C@@H](O)[C@H](N4C(N=CN=C5NC(C6=CC=CC=C6)=O)=C5N=C4)O3)C7=CC=C(OC)C=C7)C=C1
InChIKey
QNPRMZLAAWKAPQ-GNECSJIWSA-N
Last Updated: 2025-10-17 23:05
