Compound Q&A

Are there alternatives to Abrocitinib (CAS: 1622902-68-4) in synthesis?

Answer

Abrocitinib
There are several alternatives to Abrocitinib (CAS: 1622902-68-4) in synthesis, including analogs like PF-06651607 and isomers such as 2R-isomer. Common alternative reagents include other JAK inhibitors like baricitinib or tofacitinib. Care should be taken to ensure the chosen alternative meets the desired pharmacological profile.

About

English Name Abrocitinib
Molecular Formula C14H21N5O2S
Molecular Weight 323.42 g/mol
SMILES CCCS(=O)(=O)N[C@H]1C[C@H](C1)N(c2ncnc3c2cc[nH]3)C
InChIKey IUEWXNHSKRWHDY-PHIMTYICSA-N
Last Updated: 2025-10-17 23:05

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