Compound Q&A

Are there alternatives to N-Acetyl-5'-O-[bis(4-methoxyphenyl)(phenyl)methyl]-3'-O-[(2-cyanoethoxy)(diisopropylamino)phosphino]-2'-deoxycytidine in synthesis?

Answer

N-Acetyl-5'-O-[bis(4-methoxyphenyl)(phenyl)methyl]-3'-O-[(2-cyanoethoxy)(diisopropylamino)phosphino]-2'-deoxycytidine
There are other nucleoside derivatives that can be used as alternatives to N-Acetyl-5'-O-[bis(4-methoxyphenyl)(phenyl)methyl]-3'-O-[(2-cyanoethoxy)(diisopropylamino)phosphino]-2'-deoxycytidine in synthesis. These alternatives include other acetylated nucleosides or phosphoramidites with different substituents. Common alternative reagents include acetyl derivatives of cytidine and related nucleosides, which can be synthesized using various protecting group strategies and synthetic methodologies.

About

English Name N-Acetyl-5'-O-[bis(4-methoxyphenyl)(phenyl)methyl]-3'-O-[(2-cyanoethoxy)(diisopropylamino)phosphino]-2'-deoxycytidine
Molecular Formula C41H50N5O8P
Molecular Weight 17.03 g/mol
SMILES N#CCCOP(N(C(C)C)C(C)C)O[C@@H]1C[C@H](O[C@H]1COC(c1ccc(cc1)OC)(c1ccc(cc1)OC)c1ccccc1)n1ccc(nc1=O)NC(=O)C
InChIKey MECWEBCHRKVTNV-RLWDVSNXSA-N
Last Updated: 2025-10-17 17:23

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