What regulatory guidelines apply to phosphine (CAS: 22398-80-7)?

Phosphine (CAS: 22398-80-7) falls under the scope of various regulatory guidelines including GHS classification, REACH regulations, and FDA/EPA requirements. It is classified as a flammable gas and is subject to the Globally Harmonized System of Classification and Labelling of Chemicals (GHS). Under REACH, it requires registration if manufactured or imported in quantities above 1 tonne per year. FDA and EPA have specific requirements for its handling and disposal to ensure safety and environmental protection.