Compound Q&A
How is Ethyl 3-bromo-1H-1,2,4-triazole-5-carboxylate (CAS: 774608-89-8) typically synthesized?
Answer
Ethyl 3-bromo-1H-1,2,4-triazole-5-carboxylate is usually synthesized via a bromination reaction of ethyl 1H-1,2,4-triazole-5-carboxylate with N-bromosuccinimide (NBS) or similar brominating agents. The reaction is typically conducted in the presence of a suitable solvent such as dichloromethane. The yield is about 75-80%, and the reaction is selective towards the bromination of the triazole ring.
About
CAS No
774608-89-8
English Name
Ethyl 3-bromo-1H-1,2,4-triazole-5-carboxylate
Molecular Formula
C5H6BrN3O2
Molecular Weight
220.03 g/mol
SMILES
CCOC(=O)C1=NNC(=N1)Br
InChIKey
IKUFDPUSUXPOAC-UHFFFAOYSA-N
Last Updated: 2025-10-17 07:35
