Compound Q&A

How is 5,6-Dimethoxy-2-(4-piperidinylmethyl)-1-indanone (CAS: 120014-30-4) typically synthesized?

Answer

5,6-Dimethoxy-2-(4-piperidinylmethyl)-1-indanone
5,6-Dimethoxy-2-(4-piperidinylmethyl)-1-indanone is typically synthesized by the condensation of 4-piperidinemethanol with 5,6-dimethoxy-1-indanone in the presence of a mild base like triethylamine. The reaction is carried out at room temperature, and the product is isolated by recrystallization from ethanol. The yield is usually around 75-85%.

About

English Name 5,6-Dimethoxy-2-(4-piperidinylmethyl)-1-indanone
Molecular Formula C17H23NO3
Molecular Weight 289.38 g/mol
SMILES COC1=C(C=C2C(=C1)CC(C2=O)CC3CCNCC3)OC
InChIKey PGBZORAISITZTF-UHFFFAOYSA-N
Last Updated: 2025-10-17 07:35

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