Compound Q&A

How is (2-Chloro-4-fluorophenyl)hydrazine hydrochloride (CAS: 497959-29-2) typically synthesized?

Answer

(2-Chloro-4-fluorophenyl)hydrazine hydrochloride (1:1)
(2-Chloro-4-fluorophenyl)hydrazine hydrochloride (CAS: 497959-29-2) is typically synthesized via the condensation of 2-chloro-4-fluorophenyl isocyanate with hydrazine hydrochloride. The reaction is usually carried out in a solvent like methanol, with a yield of around 85%. The process requires careful temperature control to prevent side reactions.

About

English Name (2-Chloro-4-fluorophenyl)hydrazine hydrochloride (1:1)
Molecular Formula C6H7Cl2FN2
Molecular Weight 197.04 g/mol
SMILES C1=CC(=C(C=C1F)Cl)NN.Cl
InChIKey QELCWIMDZKOJBU-UHFFFAOYSA-N
Last Updated: 2025-10-17 07:35

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