Compound Q&A
How is 3-(1-Benzothiophen-3-yl)-N-[(9H-fluoren-9-ylmethoxy)carbonyl]-L-alanine (CAS: 177966-60-8) typically synthesized?
Answer
![3-(1-Benzothiophen-3-yl)-N-[(9H-fluoren-9-ylmethoxy)carbonyl]-L-alanine](https://static.chemtradehub.com/structs/177/177966-60-8-d5b6.webp "3-(1-Benzothiophen-3-yl)-N-[(9H-fluoren-9-ylmethoxy)carbonyl]-L-alanine")
3-(1-Benzothiophen-3-yl)-N-[(9H-fluoren-9-ylmethoxy)carbonyl]-L-alanine (CAS: 177966-60-8) is typically synthesized through a multi-step process involving the condensation of 1-benzothiophen-3-ylalanine with fluoren-9-ylmethanol, followed by a coupling reaction using a suitable coupling agent like HATU in the presence of a base. The reaction is performed under anhydrous conditions to ensure high reactivity and yield.
About
CAS No
177966-60-8
English Name
3-(1-Benzothiophen-3-yl)-N-[(9H-fluoren-9-ylmethoxy)carbonyl]-L-alanine
Molecular Formula
C26H21NO4S
Molecular Weight
443.52 g/mol
SMILES
C1=CC=C2C(=C1)C(C3=CC=CC=C32)COC(=O)NC(CC4=CSC5=CC=CC=C54)C(=O)O
InChIKey
BQIZNDWONIMCGM-QHCPKHFHSA-N
Last Updated: 2025-10-17 07:35
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