Compound Q&A

How is 3-(Aminomethyl)-5-methylhexanoic acid (CAS: 128013-69-4) typically synthesized?

Answer

3-(Aminomethyl)-5-methylhexanoic acid
3-(Aminomethyl)-5-methylhexanoic acid is typically synthesized via a multi-step process involving the protection of an amino group, followed by a condensation reaction with a carboxylic acid derivative. Commonly, the amino group is protected using tert-butyloxycarbonyl (Boc) or benzyloxycarbonyl (Z) groups. The protected intermediate is then reacted with 5-methylhexanoic acid chloride or an equivalent derivative under anhydrous conditions, followed by deprotection to yield the desired product. This method provides good yield and selectivity.

About

English Name 3-(Aminomethyl)-5-methylhexanoic acid
Molecular Formula C8H17NO2
Molecular Weight 159.23 g/mol
SMILES CC(C)CC(CC(=O)O)CN
InChIKey AYXYPKUFHZROOJ-UHFFFAOYSA-N
Last Updated: 2025-10-16 16:48

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