Compound Q&A

How is 2-[(1R,5S)-6,6-dimethylbicyclo[3.1.1]hept-2-en-2-yl]ethan-1-ol (CAS: 35836-73-8) typically synthesized?

Answer

2-[(1R,5S)-6,6-dimethylbicyclo[3.1.1]hept-2-en-2-yl]ethan-1-ol
2-[(1R,5S)-6,6-dimethylbicyclo[3.1.1]hept-2-en-2-yl]ethan-1-ol is synthesized through a multi-step process involving the synthesis of the bicyclic ketone followed by its reduction to the alcohol. Common methods include the Wittig reaction, Grignard reagent addition, or catalytic hydrogenation. The overall yield is around 70-80%, with high selectivity towards the desired product.

About

CAS No 35836-73-8
English Name 2-[(1R,5S)-6,6-dimethylbicyclo[3.1.1]hept-2-en-2-yl]ethan-1-ol
Molecular Formula C11H18O
Molecular Weight 166.26 g/mol
SMILES CC1(C2CC=C(C1C2)CCO)C
InChIKey ROKSAUSPJGWCSM-UWVGGRQHSA-N
Last Updated: 2025-10-16 16:48

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