Compound Q&A
How is 1-Methyl-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-indole (CAS: 837392-62-8) typically synthesized?
Answer
1-Methyl-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-indole is typically synthesized via a boronation reaction of 1-methyl-1H-indole with 4,4,5,5-tetramethyl-2-bora-1,3,2-dioxaborine. The reaction requires a palladium catalyst and a base such as potassium carbonate. The yield is generally good, and the reaction is considered to be a mild and efficient method for the preparation of this compound.
About
CAS No
837392-62-8
English Name
1-Methyl-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-indole
Molecular Formula
C15H20BNO2
Molecular Weight
257.14 g/mol
SMILES
B1(OC(C(O1)(C)C)(C)C)C2=CC3=C(C=C2)N(C=C3)C
InChIKey
JQLYKUPEQYNDFF-UHFFFAOYSA-N
Last Updated: 2025-10-16 16:48
