Compound Q&A

How is 4,6-Dimethoxy-2-methylpyrimidine (CAS: 13566-48-8) typically synthesized?

Answer

4,6-Dimethoxy-2-methylpyrimidine
4,6-Dimethoxy-2-methylpyrimidine is commonly synthesized via the reaction of 2-methylpyrimidine with methanol under acidic conditions. The synthesis involves the methylation of the pyrimidine at the 2, 4, and 6 positions, with high selectivity and good yield. The process often uses catalytic amounts of acid like hydrochloric acid or sulfuric acid.

About

CAS No 13566-48-8
English Name 4,6-Dimethoxy-2-methylpyrimidine
Molecular Formula C7H10N2O2
Molecular Weight 154.17 g/mol
SMILES CC1=NC(=CC(=N1)OC)OC
InChIKey FWQJAXMTUACMLK-UHFFFAOYSA-N
Last Updated: 2025-10-16 16:48

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