Compound Q&A

How is Methyl 1H-indol-3-ylacetate (CAS: 1912-33-0) typically synthesized?

Answer

Methyl 1H-indol-3-ylacetate
Methyl 1H-indol-3-ylacetate (CAS: 1912-33-0) is typically synthesized via a condensation reaction between indole and acetic anhydride. The reaction is catalyzed by an acid, such as sulfuric acid, and proceeds with moderate to good yield. Selectivity is high, and the product is purified by recrystallization.

About

CAS No 1912-33-0
English Name Methyl 1H-indol-3-ylacetate
Molecular Formula C11H11NO2
Molecular Weight 189.21 g/mol
SMILES COC(=O)CC1=CNC2=CC=CC=C21
InChIKey KTHADMDGDNYQRX-UHFFFAOYSA-N
Last Updated: 2025-10-16 16:48

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