Compound Q&A

How is (4S,4As,5ar,12as)-4,7-bis(dimethylamino)-3,10,12,12a-tetrahydroxy-1,11-dioxo-4a,5,5a,6-tetrahydro-4h-tetracene-2-carboxamide dihydrochloride (CAS: 10118-90-8) typically synthesized?

Answer

(4S,4As,5ar,12as)-4,7-bis(dimethylamino)-3,10,12,12a-tetrahydroxy-1,11-dioxo-4a,5,5a,6-tetrahydro-4h-tetracene-2-carboxamide dihydrochloride
This compound is typically synthesized via a multi-step process involving the condensation of a tetracene derivative with dimethylamine, followed by hydroxylation and amidation steps. Key catalysts and reagents include palladium and various oxidants. The process yields high-quality products with good selectivity and yield.

About

CAS No 10118-90-8
English Name (4S,4As,5ar,12as)-4,7-bis(dimethylamino)-3,10,12,12a-tetrahydroxy-1,11-dioxo-4a,5,5a,6-tetrahydro-4h-tetracene-2-carboxamide dihydrochloride
Molecular Formula C23H27N3O7
Molecular Weight 457.48 g/mol
SMILES CN(C)C1C2CC3CC4=C(C=CC(=C4C(=C3C(=O)C2(C(=C(C1=O)C(=O)N)O)O)O)O)N(C)C
InChIKey DYKFCLLONBREIL-KVUCHLLUSA-N
Last Updated: 2025-10-16 16:48

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