Compound Q&A
How is 2,4,5-Trifluorobenzyl Chloride (CAS: 243139-71-1) typically synthesized?
Answer
2,4,5-Trifluorobenzyl Chloride (CAS: 243139-71-1) is typically synthesized by Friedel-Crafts alkylation of 2,4,5-trifluorobenzenesulfonyl chloride with benzyl chloride, followed by decarboxylation. This reaction is often catalyzed by aluminum chloride and proceeds with good regioselectivity and high yield.
About
CAS No
243139-71-1
English Name
2,4,5-Trifluorobenzyl Chloride
Molecular Formula
C7H4ClF3
Molecular Weight
180.56 g/mol
SMILES
C1=C(C(=CC(=C1F)F)F)CCl
InChIKey
JMXPOOVDUVHJRO-UHFFFAOYSA-N
Last Updated: 2025-10-16 16:48
