Compound Q&A

How is 2,1,3-Benzothiadiazol-4-amine (CAS: 767-64-6) typically synthesized?

Answer

2,1,3-Benzothiadiazol-4-amine
2,1,3-Benzothiadiazol-4-amine is typically synthesized by the reduction of 2,1,3-benzothiadiazolone with a reducing agent such as sodium borohydride or lithium aluminum hydride. The reaction is carried out in an inert solvent like dimethylformamide (DMF) at room temperature. The yield is generally good, around 80-90%, and the product can be isolated by filtration and recrystallization.

About

CAS No 767-64-6
English Name 2,1,3-Benzothiadiazol-4-amine
Molecular Formula C6H5N3S
Molecular Weight 151.19400000000002 g/mol
SMILES C1=CC2=NSN=C2C(=C1)N
InChIKey DRLGIZIAMHIQHL-UHFFFAOYSA-N
Last Updated: 2025-10-16 16:48

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