Compound Q&A
How is 4-Chloro-5-fluoro-2-methylpyrimidine (CAS: 898044-50-3) typically synthesized?
Answer
4-Chloro-5-fluoro-2-methylpyrimidine is usually synthesized via the reaction of 2-chloro-5-fluoropyrimidine with methylamine. The reaction is typically carried out in the presence of a base like sodium hydride to improve yield and selectivity. The exact conditions can vary, but the yield is often around 70-80%.
About
CAS No
898044-50-3
English Name
4-Chloro-5-fluoro-2-methylpyrimidine
Molecular Formula
C5H4ClFN2
Molecular Weight
146.55 g/mol
SMILES
CC1=NC=C(C(=N1)Cl)F
InChIKey
QSFGQHQXDKLATK-UHFFFAOYSA-N
Last Updated: 2025-10-16 16:48
