Compound Q&A

Are there alternatives to (2R,3S,5S)-5-(4-amino-7H-pyrrolo[2,3-d]pyrimidin-7-yl)-2-(hydroxymethyl)tetrahydrofuran-3-ol (CAS: 60129-59-1) in synthesis?

Answer

(2R,3S,5S)-5-(4-amino-7H-pyrrolo[2,3-d]pyrimidin-7-yl)-2-(hydroxymethyl)tetrahydrofuran-3-ol
Alternatives to this compound include other pyrimidine-based analogs such as 5-(4-amino-7H-pyrrolo[2,3-d]pyrimidin-7-yl)-2-hydroxymethyltetrahydrofuran-3-ol derivatives. Isomers like (2S,3R,5S)- and (2S,3S,5R)-isomers can also be used, and common alternative reagents in synthesis might include 2,3-dihydrofuran-2-carbaldehyde and 4-amino-7H-pyrrolo[2,3-d]pyrimidine-7-carbaldehyde.

About

CAS No 60129-59-1
English Name (2R,3S,5S)-5-(4-amino-7H-pyrrolo[2,3-d]pyrimidin-7-yl)-2-(hydroxymethyl)tetrahydrofuran-3-ol
Molecular Formula C11H14N4O3
Molecular Weight 250.26 g/mol
SMILES NC1=C2C(N([C@@H]3C[C@@H]([C@@H](CO)O3)O)C=C2)=NC=N1
InChIKey NIJSNUNKSPLDTO-YIZRAAEISA-N
Last Updated: 2025-10-14 19:01

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