Compound Q&A

Are there alternatives to 5'-O-[Bis(4-methoxyphenyl)(phenyl)methyl]-3'-O-[(2-cyanoethoxy)(diisopropylamino)phosphino]-2'-deoxy-2'-fluorouridine in synthesis?

Answer

5'-O-[Bis(4-methoxyphenyl)(phenyl)methyl]-3'-O-[(2-cyanoethoxy)(diisopropylamino)phosphino]-2'-deoxy-2'-fluorouridine
In the synthesis of nucleosides, there are various alternatives to 5'-O-[Bis(4-methoxyphenyl)(phenyl)methyl]-3'-O-[(2-cyanoethoxy)(diisopropylamino)phosphino]-2'-deoxy-2'-fluorouridine. Common alternatives include different protecting groups and substituents, such as other alkyl derivatives or isosteric analogs. These can be chosen based on the specific requirements of the synthesis and desired properties of the final product.

About

English Name 5'-O-[Bis(4-methoxyphenyl)(phenyl)methyl]-3'-O-[(2-cyanoethoxy)(diisopropylamino)phosphino]-2'-deoxy-2'-fluorouridine
Molecular Formula C39H46FN4O8P
Molecular Weight 748.8 g/mol
SMILES CC(C)N(C(C)C)P(OCCC#N)OC1C(OC(C1F)N2C=CC(=O)NC2=O)COC(C3=CC=CC=C3)(C4=CC=C(C=C4)OC)C5=CC=C(C=C5)OC
InChIKey HQHQPAYRJJMYQX-DJTPZYMWSA-N
Last Updated: 2025-10-14 19:01

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