Compound Q&A

How is Purmorphamine (CAS: 483367-10-8) typically synthesized?

Answer

Purmorphamine
Purmorphamine is synthesized through a multi-step process involving the condensation of 2-aminobenzoxazole and 2,3-dihydro-1H-inden-1-one. Commonly used catalysts include palladium(II) acetate and triphenylphosphine. The overall yield is moderate, and the method provides good selectivity for the desired product.

About

English Name Purmorphamine
Molecular Formula C31H32N6O2
Molecular Weight 520.64 g/mol
SMILES C1CCC(CC1)n1cnc2c1nc(nc2Nc1ccc(cc1)N1CCOCC1)Oc1cccc2c1cccc2
InChIKey FYBHCRQFSFYWPY-UHFFFAOYSA-N
Last Updated: 2025-10-13 19:39

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