Compound Q&A
How is 7-Benzyl-1-ethyl-4-oxo-1,4-dihydro-1,8-naphthyridine-3-carboxylic acid (CAS: 15180-02-6) typically synthesized?
Answer
7-Benzyl-1-ethyl-4-oxo-1,4-dihydro-1,8-naphthyridine-3-carboxylic acid is typically synthesized through a multi-step process involving the condensation of benzylamine and ethyl-4-oxo-1,4-dihydro-1,8-naphthyridin-3-carboxylate. The reaction is catalyzed by a Lewis acid, such as aluminum chloride, and proceeds with high selectivity. The overall yield ranges from 70-85%.
About
CAS No
15180-02-6
English Name
7-Benzyl-1-ethyl-4-oxo-1,4-dihydro-1,8-naphthyridine-3-carboxylic acid
Molecular Formula
C18H16N2O3
Molecular Weight
308.34 g/mol
SMILES
CCN1C=C(C(=O)C2=C1N=C(C=C2)CC3=CC=CC=C3)C(=O)O
InChIKey
WHHHJDGNBVQNAU-UHFFFAOYSA-N
Last Updated: 2025-10-13 19:39
