Compound Q&A

How is N~2~-2-Naphthylglutamine (CAS: 14525-44-1) typically synthesized?

Answer

N~2~-2-Naphthylglutamine
N~2~-2-Naphthylglutamine is typically synthesized via the condensation of 2-naphthylamine with glutaric anhydride in the presence of a catalyst such as p-toluenesulfonic acid. The reaction yields a 90% to 95% selectivity towards the desired product and a good yield (70% to 80%).

About

CAS No 14525-44-1
English Name N~2~-2-Naphthylglutamine
Molecular Formula C15H16N2O3
Molecular Weight 272.3 g/mol
SMILES C1=CC=C2C=C(C=CC2=C1)NC(=O)CCC(C(=O)O)N
InChIKey LRSCKKDFEZPTFH-UHFFFAOYSA-N
Last Updated: 2025-10-13 19:39

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