Compound Q&A

How is 2-(3,4-Dihydroxyphenyl)-3,5,6,7-tetrahydroxy-4H-chromen-4-one (CAS: 90-18-6) typically synthesized?

Answer

2-(3,4-Dihydroxyphenyl)-3,5,6,7-tetrahydroxy-4H-chromen-4-one
2-(3,4-Dihydroxyphenyl)-3,5,6,7-tetrahydroxy-4H-chromen-4-one is commonly synthesized via the Claisen-Schmidt condensation of 3,4-dihydroxybenzaldehyde with 3,4-dihydroxybenzyl alcohol in the presence of base, such as potassium carbonate. The reaction is carried out in an aprotic solvent like dimethylformamide (DMF) at room temperature. The yield is typically in the range of 70-90%, depending on the purity of starting materials and reaction conditions.

About

CAS No 90-18-6
English Name 2-(3,4-Dihydroxyphenyl)-3,5,6,7-tetrahydroxy-4H-chromen-4-one
Molecular Formula C15H10O8
Molecular Weight 318.24 g/mol
SMILES c1cc(c(cc1c2c(c(=O)c3c(o2)cc(c(c3O)O)O)O)O)O
InChIKey ZVOLCUVKHLEPEV-UHFFFAOYSA-N
Last Updated: 2025-10-13 19:39

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