Compound Q&A
How is 5-trityl-4,6,7,7a-tetrahydrothieno[3,2-c]pyridin-2-one (CAS: 109904-26-9) typically synthesized?
Answer
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5-trityl-4,6,7,7a-tetrahydrothieno[3,2-c]pyridin-2-one can be synthesized via a multistep process involving the condensation of 4,6,7,7a-tetrahydrothieno[3,2-c]pyridin-2-one with trityl chloride in the presence of a base such as triethylamine. The reaction is carried out under anhydrous conditions, typically in dichloromethane. The yield is usually around 75-80%, with good regioselectivity and high purity.
About
CAS No
109904-26-9
English Name
5-trityl-4,6,7,7a-tetrahydrothieno[3,2-c]pyridin-2-one
Molecular Formula
C26H23NOS
Molecular Weight
397.54 g/mol
SMILES
C1CN(CC2=CC(=O)SC21)C(C3=CC=CC=C3)(C4=CC=CC=C4)C5=CC=CC=C5
InChIKey
QWWKINCXTMBNIV-UHFFFAOYSA-N
Last Updated: 2025-10-13 19:39
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