Compound Q&A

How is phenyl isocyanide (CAS: 931-54-4) typically synthesized?

Answer

Phenyl isocyanide
Phenyl isocyanide can be synthesized by the reaction of phenyl isothiocyanate with sodium hydroxide, followed by acidification to form phenyl isocyanide. The reaction is typically carried out in a water medium, and the yield is around 80-85%. This method uses sodium hydroxide as a catalyst and requires appropriate safety measures to handle the strong base and the subsequent acidification step.

About

CAS No 931-54-4
English Name Phenyl isocyanide
Molecular Formula C7H5N
Molecular Weight 12.01 g/mol
SMILES [C-]#[N+]C1=CC=CC=C1
InChIKey RCIBIGQXGCBBCT-UHFFFAOYSA-N
Last Updated: 2025-10-13 17:50

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