Compound Q&A

How is 1-Chloro-3-fluoro-5-nitrobenzene (CAS: 4815-64-9) typically synthesized?

Answer

1-Chloro-3-fluoro-5-nitrobenzene
1-Chloro-3-fluoro-5-nitrobenzene (CAS: 4815-64-9) can be synthesized through the nitration of 1-chloro-3-fluorobenzene. This process typically involves the use of a mixture of nitric acid and sulfuric acid as the nitrating agent. The yield is approximately 85%, and the selectivity towards the 5-nitro position is very high.

About

CAS No 4815-64-9
English Name 1-Chloro-3-fluoro-5-nitrobenzene
Molecular Formula C6H3ClFNO2
Molecular Weight 175.546 g/mol
SMILES C1=C(C=C(C=C1F)Cl)[N+](=O)[O-]
InChIKey TZAGKOKYKROSOW-UHFFFAOYSA-N
Last Updated: 2025-10-13 17:50

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