Compound Q&A
How is Methyl 5-formyl-3-thiophenecarboxylate (CAS: 67808-66-6) typically synthesized?
Answer
Methyl 5-formyl-3-thiophenecarboxylate can be synthesized through the reaction of thiophene-3-carboxylic acid and methanol in the presence of a strong acid catalyst like sulfuric acid. The reaction involves esterification, where the carboxylic acid group reacts with methanol to form the methyl ester derivative. The yield of the product is typically around 85%, and the process is carried out under heating conditions to enhance the reaction rate.
About
CAS No
67808-66-6
English Name
Methyl 5-formyl-3-thiophenecarboxylate
Molecular Formula
C7H6O3S
Molecular Weight
170.189 g/mol
SMILES
COC(=O)C1=CSC(=C1)C=O
InChIKey
GNXNZRYWBFMVHK-UHFFFAOYSA-N
Last Updated: 2025-10-13 17:50
