Compound Q&A

How is Methyl 5-hydroxynicotinate (CAS: 30766-22-4) typically synthesized?

Answer

Methyl 5-hydroxynicotinate
Methyl 5-hydroxynicotinate is commonly synthesized by the hydroxylation of nicotinic acid followed by esterification with methyl alcohol. The reaction typically uses a hydrogenation catalyst like platinum or palladium on charcoal. The yield can be enhanced by optimizing the reaction conditions such as temperature, pressure, and the use of appropriate solvents.

About

CAS No 30766-22-4
English Name Methyl 5-hydroxynicotinate
Molecular Formula C7H7NO3
Molecular Weight 153.14 g/mol
SMILES COC(=O)C1=CC(=CN=C1)O
InChIKey KJJSHOHQQHACLE-UHFFFAOYSA-N
Last Updated: 2025-10-13 15:08

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