Compound Q&A
How is 6-Fluoro-1-benzothiophene (CAS: 205055-10-3) typically synthesized?
Answer
6-Fluoro-1-benzothiophene can be synthesized via the electrophilic fluorination of benzothiophene using fluorine gas in the presence of a Lewis acid catalyst, such as ferric chloride. Another method involves the Suzuki coupling of bromobenzothiophene with a fluoroiodide in the presence of a palladium catalyst. These methods provide good yield and selectivity, making them suitable for industrial applications.
About
CAS No
205055-10-3
English Name
6-Fluoro-1-benzothiophene
Molecular Formula
C8H5FS
Molecular Weight
152.19299999999998 g/mol
SMILES
C1=CC(=CC2=C1C=CS2)F
InChIKey
IAWIFBMBSZRKGZ-UHFFFAOYSA-N
Last Updated: 2025-10-13 15:08
